Abstract
The reductive alkylation of 3,4-disubstituted pyridines is reported using either sodium in ammonia or ammonia free conditions (Na, naphthalene, THF). This partial reduction process works cleanly and efficiently giving good yields of highly functionalised dihydropyridine templates. Radical cyclisation reactions were performed on these dihydropyridines and gave fused 2- and 3-ring heterocycles with defined stereochemistry.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
