Abstract

232 strains of Escherichia coli isolated from patients in a mental hospital during an outbreak of Shigella flexneri infection, and 300 strains of E. coli from a more normal population, were examined for resistance to antibacterial drugs, for colicinogeny, and for the carriage of transfer factors. 78 (33.8%) of the strains from the hospital community were resistant to one or more antibacterial agents, and, of these strains, 49 could transfer their resistance to E. coli K12 or Salmonella typhimuriumin mixed culture. 72 (24%) of the 300 strains from the general population were also drug-resistant, and 31 of these carried transferable resistance. In both populations, approximately 3% of the strains carried transfer factors not associated with drug-resistance or colicinogeny.

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