Transfer of latissimus dorsi muscle for the functional reconstruction of quadriceps femoris muscle following oncological resection of sarcoma in the thigh

Abstract

Wide resection of tumours in the anterior compartment of the thigh frequently requires en bloc removal of the quadriceps femoris muscle. Such resection can result in significantly decreased muscle power of knee extension. Functional muscle transfer is a beneficial tool for the reconstruction process. Until now, however, there have been few reports on the outcome of quadriceps muscle reconstruction using free innervated muscle transfer. We reviewed 14 patients (seven women and seven men, mean age 53 years). The extent of tumour invasion required resection of the entire quadriceps in four cases, of three heads in six cases and of two heads in the remaining four cases. Local recurrence occurred in one patient only, and there were no major complications. In the four patients with entire resection of the quadriceps, the postoperative muscle manual test (MMT) result was 0-1 (mean, 0.5), but this recovered to between 2 and 3 (mean 2.3) after a mean follow-up of 70 months. In the six cases with resection of three heads, the MMT test result was 2 and active knee extension recovered almost fully. Transfer of free, functional latissimus dorsi muscle is best indicated for cases in which the entire quadriceps or three heads are resected. Active knee extension can be expected to improve to an MMT score of 2 after reinnervation of the transferred muscle. Microsurgical reconstruction following resection of soft-tissue sarcoma provides adequate functional and coverage reconstruction, together with better local control by allowing wider surgical margins.