Abstract

It is well known that Bacteroides fragilisand related species produce several kinds of beta-lactamases such as oxyiminocephalosporinase, penicillinase, and metallo-beta-lactamase, with some strains showing a particularly high resistance to beta-lactam antibiotics. Until now, there have only been scattered reports about the transfer of beta-lactam resistance among Bacteroides. Beta-lactam resistance in Bacteroidesseemed to be mobilized by a group of tetracycline resistance transfer elements as discussed in Chapter 35. However, we have found that B. fragiliscould transfer beta-lactam resistances in the absence of such transfer elements.

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