Abstract
Hemoglobin is a tetrameric molecule consisting of two identical αβ dimers which assemble into either of two quaternary structures, T or R. Recent studies on mutant and partially ligated hemoglobins have revealed that cooperativity exists between the α and the β hemes of each dimeric half-molecule and have led to a symmetry rule for quaternary T→R switching: the quaternary R structure is energetically favored over the T structure when each dimeric half-molecule contains at least one ligated subunit.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
