Abstract
AbstractEphedrine, often used in the treatment of asthma, is a good candidate for development of its transdermal therapeutic system. This investigation reports the design of polymeric matrix type transdermal films of ephedrine and its hydrochloride salt. The films possessing appropriate physico-chemical qualities were tested for in vitko and in vivo drug diffusion pattern, stability and skin irritation. The films were found to be free from skin irritation and stable at room temperature but adversely affected by extremes of humidity or high temperature. Both systems gave adequate release of drug and diffusion through skin into systemic circulation when tested on human volunteers.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
