Abstract
22 studies lasting 3-6h were performed on 10 newborn infants with respiratory illnesses to assess the accuracy of a transcutaneous electrochemical sensor designed by us to estimate PaO2 and PaCO2 simultaneously. The sensor was calibrated in vitro and in vivo. tcPO2 was compared with PaO2 recorded by a Searle intravascular electrode or by a Drager transcutaneous electrode that we have previously shown to give an accurate estimate of PaO2. tcPCO2 was compared with the PaCO2 of samples of arterial blood. The relation between tcPO2 and PaO2 after in vitro calibration was tcPO2 = 0.95 PaO2 + 11.93 (r = 0.69, p<0.001) and after in vivo calibration tcPO2 = 1.00 PaO2 + 1.27 (r = 0.89, p < 0.001). After in vitro calibration tcPCO2 = 0.99 PaCO2 + 9.88 (r = 0.89, p < 0.001) and after in vivo calibration tcPCO2 = 0.98 PaCO2 - 2.33 (r = 0.97, p < 0.001). We conclude that PaO2 and PaCO2 could be estimated transcutaneously by the sensor and chat the accuracy of estimation was improved by in vivo calibration.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
