Abstract
Fibromyalgia is a condition defined by chronic widespread pain and associated with central excitability and loss of descending inhibition. Pain associated with fibromyalgia interferes with daily function. TENS produces its effects primarily by reducing central excitability and activating descending inhibitory pathways. The primary objective of this study was to test the effect of TENS on pain, function and descending inhibition in people with fibromyalgia. The study used a crossover design of 43 Fibromyalgia patients (42F; 1M), aged 25-76 years (mean 49.2 ± 12.9yrs) with random assignment to three treatments: Active TENS (100 Hz, 200 μs), Placebo TENS and No Treatment Control.
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