Abstract
Transcription of pericentromeric tandemly repeated DNA transcripts in human preovulatory oocytes
Highlights
The aim of the study was to check the presence of pericentromeric TR transcripts in preovulatory oocytes and to reveal its intracellular distribution
The colocalisation of HS3 DNA and RNA with RNA-helicase p68 (DDX5) involved in the HS3 transcription regulation was estimated by immunoFISH
The GV and MI preovulatory oocytes were obtained from donors after the informed consent had been signed
Summary
Transcription of pericentromeric tandemly repeated DNA transcripts in human preovulatory oocytes 1 Institute of Cytology RAS, St. Petersburg, Russia; 2 St. Petersburg State University, Russia; 3 ART Hospital AvaPeter-Scandinavia nie@newmail.ru N 3 the non-coding DNA is repeats either scattered through genome (dispersed repeats) or tandemly organized (tandem repeats, TR or satellite DNA). These repeats are transcribed and the transcripts are involved in different processes including early preimplantation embryogenesis.
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