Abstract

In this report, we will consider several of the aspects of transcription and translation which are unique to eukaryotic cells. As our knowledge of the macromolecular biochemistry of higher organisms grows, it is apparent that the models of regulatory mechanisms derived from prokaryotes are increasingly unsatisfactory. In this report, we will summarize some of the findings in our laboratory which deal with the unique properties of the systems which transcribe DNA and regulate translation in mammalian cells.

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