Abstract
AbstractTraining of skilled movements leads to typical changes in motor evoked potentials (MEPs). To see how such changes are related to motor performance and hand preference, a goal-directed movement task was implemented on a haptic interface. Both hands of right-handed subjects were trained separately in two sessions. Transcranial magnetic stimulation (TMS) was applied contralaterally to the trained hand before and after each session. Effects of right hand training: after session #1 MEP-facilitation was 60 %, intracortical inhibition (ICI) and facilitation (ICF) were reduced and task improvement was 37%. Left hand training: after session #1 MEP-facilitation was +59%, ICI and ICF remained unchanged and task improvement was +30%. During session #2 all variables for both sides remained constant. The different time course of the training-induced effects for the left and right hemisphere obviously reflects functional side differences in hand motor control.Keywordsskill acquisitionuse-dependent plasticityhemispheric differencestranscranial magnetic stimulationvirtual realityhaptic training
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