Abstract
Twenty-five patients underwent transcranial Doppler and single photon emission tomography within 6 h of the onset of symptoms of a first-ever acute hemispheric brain infarction, and 1 week later. Quantitative data analysis was performed upon perfusion data and blood flow velocity in middle cerebral arteries and the cerebral hemispheres. Middle cerebral artery flow velocity was abnormal in 15 of 25 cases. Cerebral blood flow was abnormal in 18 of 25 middle cerebral artery regions. A high correlation was found between middle cerebral artery flow velocity and perfusion, both in the middle cerebral artery region (r = 0.63, p < 0.001) and in the hemisphere (r = 0.59, p < 0.002); these relationships persisted at 1 week. The results show that transcranial Doppler accurately reflects the state of cerebral perfusion in the very early stages of stroke.
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