Abstract
Transcranial direct current stimulation enhances recovery from motor deficits following hypoxia-ischemia in neonatal rats
Highlights
Stroke is defined as permanent brain damage due to obstruction of blood or oxygen to the brain
We show that transcranial direct current stimulation (tDCS) has a neurophysiological effect on the neonatal rat brain after HI insult, with promising outcomes showing improvement in motor function after stimulation
We can conclude that chronic tDCS treatment is innocuous and improves motor deficits associated with HI injury, with the tDCS treated rat pups showing improvement in overall movement ability, strength, and weight gain
Summary
Stroke is defined as permanent brain damage due to obstruction of blood or oxygen to the brain. It is known that neonatal strokes are recognized in about 1 of 4000 live births per year [1]. Strokes that have occurred in newborns often result in life long impairments including reduced or lost control of sensory and motor functions, aphasia, seizures, learning impairments, cerebral palsy, and death. The most promising rehabilitative treatment is physical therapy (PT) [2]. Despite early PT, more a significant percentage will progress to severe motor disability that will affect their basic activities of daily living [2]. There is need for more effective rehabilitative therapies, for targeted therapies that prevent the secondary and tertiary damage processes associated with severe stroke
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
