Abstract
Background: - A ventricular septal defect is a hole or a defect in the septum that divides the 2 lower chambers of the heart, resulting in communication between the left and right ventricular cavities. Objectives: -To evaluate the efficacy and safety of percutaneous transcatheter closure of perimembranous VSD by using Amplatzer Ductal Occluder type I. Method: This is a prospective study. Total numbers of 216 patients with perimembranous VSD were enrolled for transcatheter closure of the defect by using Amplatzer Ductal Occluder type I (ADO I). The inclusion criteria of the study were: the VSD diameter ranged from 4mm to 12 mm, the VSD distance (rim) at least 2mm from atrioventricular and semilunar valves, and the systolic pulmonary atrial pressure ranged (20-75 mm Hg) with mean pulmonary atrial pressure (40 mm Hg). The patients with malalignment type of VSD were excluded from the study.
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