Transcatheter Closure of Perimembranous Ventricular Septal Defect Using the Amplatzer Duct Occluder II

Abstract

Objective: To evaluate the efficacy of Amplatzer duct occluder II (ADO II) in the treatment of perimembranous ventricular septal defect (pmVSD) in children. Methods: Between June 2017 and June 2020, 13 patients with pmVSD had attempted transcatheter closure using ADO II, seven of patients were used antegrade approach and six of them were used retrograde approach. Results: There were 8 males and 5 females, age from 1 to 7 years, weight from 10.5 to 31.0 kg, and VSD size from 2.0 to 4.0 mm. Procedure was successful in all cases with the outer diameter of the occluders ranging from 4 to 6 mm. No aortic, tricuspid regurgitation or residual shunt was found in the immediate ultrasound assessment. No arrhythmia was observed in the Holter monitoring 3 days after the intervention. Discharge echocardiography indicated complete shunt closure. No evidence of occluder prolapse, malignant arrhythmia, or intensed valve regurgitation was seen on a median follow-up of 18 months (range, 6 to 36 months). Conclusions: Based on our experience, ADO II showed good efficacy in the early and middle stages of pediatric pmVSD closures.