Abstract
Objective To estimate the transbronchial lung biopsies (TBLB) for acute rejection (AR) in lung transplant recipients. Methods A retrospective study on 50 patients who underwent transplantation between September 2002 and July 2007 was conducted, and 145 TBLB taken from these patients were reviewed. Pathologically, all patients were classified into the early AR group and early non-AR group. The positive rate of TBLB in the early diagnosis of AR after operation, the long-term incidence of AR in both groups, and the diagnostic accuracy of TBLB to AR were analyzed. Results The incidence of AR in early period was 44 % (22/50). The accuracy of the TBLB to AR was 100 %. 61.1 % of the patients with AR had no typical clinical features. Conclusions AR without typical clinical features after lung transplantation is easily misdiagnosed. TBLB has a higher accuracy in the diagnosis of AR following the lung transplantation. Key words: Lung transplantation; Bronchoscopy; Acute rejection
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