Abstract
Objective: The aim of the study was to determine the safety and effectiveness of transarterial embolization ablation (TEA) of hepatocellular carcinoma (HCC) with a lipiodol–ethanol mixture. Background: TEA is a new treatment strategy for HCC, and some researchers have reported its effectiveness in HCC. Patients and methods: This study was a prospective cohort study conducted at the National Liver Institute and Faculty of Medicine, Menoufia University, and included 40 patients having unresectable HCCs. At 3 and 6 months after TEA, triphasic computed tomography was performed, and tumor responses were assessed using a modified version of Response Evaluation Criteria in Solid Tumor (mRECIST). Results: Every case was treated. At 3 and 6 months after embolization, contrast computed tomography showed no enhancing lesions. a-Fetoprotein levels were significantly reduced (12.18 ± 15.67) at 6 months after treatment. The partial and complete responses of tumors were 12.5 and 87.5%, respectively, 6 months after treatment. The overall survival rate was 90%. Conclusion: TEA is an effective therapy for patients with unresectable HCC.
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