Transaminase – carbonic anhydrase bi-enzymatic cascade for preparation of (R)-1-arylethan-1-amines and (S)-1-arylethan-1-ols

Abstract

The cellular Pseudomonas psychrotolerans transaminase – human carbonic anhydrase II bi-enzymatic cascade efficiently convert (±)-1-phenylethan-1-amines into the corresponding enantiopure (R)-amines and (S)-1-phenylethan-1-ols.