Abstract
Rinehart and Greenberg1,2 observed a marked thickening of the intima and deposition of lipid in pyridoxine-deficient monkeys. Though the role of pyridoxine as an essential co-factor in fat and protein metabolism has been well established, the precise mechanism of atherogenesis in pyridoxine deficiency has not been elucidated. Goswami and Sadhu3 have adduced evidence tending to show that the hyper -cholesterolæmia of pyridoxine deficiency is not related to impairment of formation of arachidonic acid. The possibility that atherogenesis may be a consequence of defective formation and maintenance of collagen and elastic tissue brought about by decreased trans-aminase activity therefore gains added importance. However, while the transaminase activities of several tissues, both under normal and pathological conditions, have been examined, very little work has been reported on the transaminase activity of arterial tissue. The present communication reports the demonstration of significant transaminase activity in arterial tissue.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
