Abstract
The role of TVA in suppressing proliferation of various human cancer cell lines was investigated that TVA and c9, t11-CLA both suppressed cell proliferation. The suppressive effect of TVA was clearly observed in T47D breast carcinoma cells after stearoyl-CoA desaturase-1 (SCD) knockdown using small interfering RNA (siRNA), demonstrating TVA directly affects suppression of human breast carcinogenesis.
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