Abstract

This study is to test the feasibility of using trans-pars-planar illumination for ultra-wide field pediatric fundus photography. Fundus examination of the peripheral retina is essential for clinical management of pediatric eye diseases. However, current pediatric fundus cameras with traditional trans-pupillary illumination provide a limited field of view (FOV), making it difficult to access the peripheral retina adequately for a comprehensive assessment of eye conditions. Here, we report the first demonstration of trans-pars-planar illumination in ultra-wide field pediatric fundus photography. For proof-of-concept validation, all off-the-shelf optical components were selected to construct a lab prototype pediatric camera (PedCam). By freeing the entire pupil for imaging purpose only, the trans-pars-planar illumination enables a 200° FOV PedCam, allowing easy visualization of both the central and peripheral retina up to the ora serrata. A low-cost, easy-to-use ultra-wide field PedCam provides a unique opportunity to foster affordable telemedicine in rural and underserved areas.

Highlights

  • Pediatric eye diseases such as retinopathy of prematurity (ROP) and retinoblastoma can affect both the central and peripheral retina

  • Wide field fundus examination is essential for screening, diagnosis and treatment evaluation of pediatric eye diseases [1,2]

  • We demonstrate the first successful implementation of contact-mode trans-pars-planar illumination in pediatric fundus photography, with 200° field of view (FOV) in a single-shot image, allowing easy examination of the peripheral retina up to the ora serrata, i.e., the far end of the retina

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Summary

Introduction

Pediatric eye diseases such as retinopathy of prematurity (ROP) and retinoblastoma can affect both the central and peripheral retina. Wide field fundus examination is essential for screening, diagnosis and treatment evaluation of pediatric eye diseases [1,2]. In the USA alone, 400–600 infants become legally blind due to ROP each year. At least 50,000 children are blinded because of ROP each year [7]. Prompt screening and early diagnosis are essential steps to prevent visual impairment and blindness due to ROP [8]. If it could be diagnosed promptly, most of ROP caused visual losses are preventable. Routine ROP screening is challenging, in underserved areas and developing countries, where the access to both expensive instruments and skilled ophthalmologists is limited [9]

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