Abstract
Voltage gated sodium channels are membrane proteins that play a critical role in electrical signaling of excitable cells. Amongst this family, the isoform Nav1.5 is responsible for the initiation and propagation of cardiac action potentials. As most of membrane proteins, Nav1.5 is well known to be a glycoprotein with ∼5% of its total weight corresponding to carbohydrates. To date, it has been shown that Nav1.5 glycosylations such as sialylations influence biophysical properties of this channel protein.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
