Abstract
Medicinal plants are the chief components in the different oriental formulations in different traditional medical systems worldwide. As a thriving source of medicine, the medicinal plants with antituberculosis (TB) properties inspire the pharmacists to develop new drugs based on their active components or semimetabolites. In the present review, the anti-TB medicinal plants were screened from the scientific literatures, based on the botanical classification and the anti-TB activity. The obtained anti-TB medicinal plants were categorized into three different categories, viz., 159 plants critically examined with a total 335 isolated compounds, 131 plants with their crude extracts showing anti-TB activity, and 27 plants in literature with the prescribed formula by the traditional healers. Our systemic analysis on the medicinal plants can assist the discovery of novel and more efficacious anti-TB drugs.
Highlights
Traditional medicines (TM) make a vital contribution to the health care industry
The International Classification of Traditional Medicine (ICTM) was added as a new chapter into the International Classification of Diseases—11 (ICD-11) [2]. This achievement currently refers to the Traditional Chinese Medicine (TCM) alone, which opens its doors to accommodate many other thriving traditional health care philosophies prevailing globally, such as Ayurveda and Traditional African medicine (TAM)
The plants employed for treating the fever in traditional medicine have not been included, as fever is taken to be a nonspecific indication of many infections that are not restricted to TB
Summary
Traditional medicines (TM) make a vital contribution to the health care industry. The International Classification of Traditional Medicine (ICTM) was added as a new chapter into the International Classification of Diseases—11 (ICD-11) [2] This achievement currently refers to the Traditional Chinese Medicine (TCM) alone, which opens its doors to accommodate many other thriving traditional health care philosophies prevailing globally, such as Ayurveda and Traditional African medicine (TAM). There exist more than 10 million new cases of active disease and nearly 1.3 million deaths annually [5, 6] In response to this spreading route, different countries developed their own traditional anti-TB formulations during the long courses in fighting this old plaque. Investigations on the TM formulations show that the plants or herbs are the main composition of the traditional anti-TB formula, from which the active components or semimetabolites present a thriving source of new drugs. This review is to inspire the development of possible new anti-TB agents derived from plants
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