Abstract
Objective. The aim of this overview was to evaluate and summarize Cochrane reviews of traditional Chinese herbal products (TCHPs) as the treatment for coronary heart disease (CHD). Methods. We searched the Cochrane Database that was concerned with the effectiveness of TCHPs for CHD. We also searched the Cochrane Central Register of Controlled Trials. Reviews and primary studies of TCHP as the treatment of any type of CHD were included. Data were extracted according to predefined inclusion criteria by two independent reviewers. Results. Six Cochrane reviews were included. They related to a wide range of TCHPs for different types of CHD. Four reviews were concerned with angina pectoris (unstable or stable), one review was concerned with heart failure, and for acute myocardial infarction. No reviews concluded that TCHPs were definitely effective for CHD because of the weak evidence. Eight primary studies were TCHPs from CHD. These studies also maybe result in bias, but better than before. Conclusion. Several Cochrane reviews of TCHPs for the treatment of different types of CHD have recently been published. None of these reviews got definite conclusion favoring the effectiveness of TCHPs due to the weak evidence. With the improved quality of the new registered RCTs. The potential role of TCHPs in treating CHD is anticipated to be detected.
Highlights
Coronary heart disease (CHD) is one of the most dangerous threats to human health, manifested by different clinical types such as angina pectoris, myocardial infarction, heart failure, cardiac arrhythmia, and so forth
Some Cochrane systematic reviews of traditional Chinese herbal products (TCHPs) for CHD have been conducted in recent years
These reviews provide preliminary evidence of TCHPs benefits to certain CHD patient populations, which call for a comprehensive evaluation on the effectiveness of TCHPs in CHD patients
Summary
Coronary heart disease (CHD) is one of the most dangerous threats to human health, manifested by different clinical types such as angina pectoris, myocardial infarction, heart failure, cardiac arrhythmia, and so forth. Cochrane reviews are regarded as the highest standard of evidence [6] They adopt transparent and comprehensive methods of finding all of the relevant evidence. Some Cochrane systematic reviews of traditional Chinese herbal products (TCHPs) for CHD have been conducted in recent years. These reviews provide preliminary evidence of TCHPs benefits to certain CHD patient populations, which call for a comprehensive evaluation on the effectiveness of TCHPs in CHD patients. This overview aims to evaluate and summarize all Cochrane reviews of TCHP as a treatment of CHD critically
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