Tracking the intrusion of unwanted memories into awareness with event-related potentials

Robin Hellerstedt,Mikael Johansson,Michael C Anderson

doi:10.1016/j.neuropsychologia.2016.07.008

Robin Hellerstedt, Mikael Johansson + Show 1 more

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https://doi.org/10.1016/j.neuropsychologia.2016.07.008

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Abstract

Involuntary retrieval of unwanted memories is a common symptom in several clinical disorders, including post-traumatic stress disorder. With an aim to track the temporal dynamics of such memory intrusions, we recorded electrophysiological measures of brain activity while participants engaged in a Think/No-Think task. We presented the left hand word (the cue) of previously encoded word pairs in green or red font. We asked participants to think of the associated right hand word (the associate) when the cue appeared in green (Think condition) and to avoid thinking of the associate when the cue appeared in red (No-Think condition). To isolate cases when participants experienced an intrusive memory, at the end of each trial, participants judged whether the response had come to mind; we classified memories that came to mind during No-Think trials, despite efforts to stop retrieval, as intrusions. In an event-related potential (ERP) analysis, we observed a negative going slow wave (NSW) effect that indexed the duration of a trace in mnemonic awareness; whereas voluntary retrieval and maintenance of the associate was related to a sustained NSW that lasted throughout the 3-s recording epoch, memory intrusions generated short-lived NSWs that were rapidly truncated. Based on these findings, we hypothesize that the intrusion-NSW reflects the associate briefly penetrating working memory. More broadly, these findings exploit the high temporal resolution of ERPs to track the online dynamics of memory intrusions.

Highlights

There are life experiences that we would rather forget
We first verified that our modified Think/No-Think protocol replicated existing behavioural findings observed in the retrieval suppression literature
We examined whether event-related potential (ERP) could allow us to track the time course of memory intrusions, and identify their similarities and differences from successful voluntary retrievals

Summary

Introduction

There are life experiences that we would rather forget Often, these episodes are well encoded in long-term memory, and when confronted with a reminder of the unwanted memory we may retrieve it involuntarily. These episodes are well encoded in long-term memory, and when confronted with a reminder of the unwanted memory we may retrieve it involuntarily Such memory intrusions are common in the general population (e.g. Rachman and de Silva, 1978) and are a key symptom of posttraumatic stress disorder (American Psychiatric Association, 2013). Refers to cases in which memories are accessed unintentionally. We use the term memory intrusion to refer to retrievals that are not merely unintentional, but that are counter-intentional. Intrusions are memories that are retrieved, despite efforts to prevent retrieval from occurring, providing a clear operational definition of involuntary access

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