Abstract

The initial physical structure of charged particle tracks plays an important role in understanding the basic mechanism of radiation action on biological material. To date, there are a number of Monte Carlo electron and ion track structure codes which have been developed independently to investigate the microscopic features of ionising radiation, the ensuing chemical pathways and the molecular nature of the damage in biomolecular targets. The paper reviews the essential input data for simulation of ionising particles and recent advances including development of new cross sections for energetic electrons and ions in water and extension of track-segment simulation to lower energies below Bragg-peak. The paper presents two examples of application of track structure in biophysical studies of ionising radiation.

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