Abstract
Primary tracheal mucosa-associated lymphoid tissue (MALT) lymphoma is extremely rare. We report a 49-year-old female patient with the complaint of dyspnea. Fiberoptic bronchoscopy showed polypoid, variable-sized and irregular nodules causing narrowing of the tracheal lumen from the proximal trachea to the left main bronchus. Because of severe stenosis in the airway and the severity of symptoms, this case was unresectable. The patient was then treated successfully with placement of an endobronchial stent through bronchofibroscopy. After the placement of the stent, bronchoscopic biopsy was performed. Pathological analysis confirms a diagnosis of MALT-associated malignant lymphoma. We performed systemic chemotherapy on the patient. The temporary stent was removed after the reduction of the stenosis. This is the first case in which tracheal MALT lymphoma was treated successfully following tracheal stent insertion guided by bronchofibroscopy. Temporary tracheal stenting can be a favorable choice for a patient with tracheal stenosis caused by primary tracheal MALT lymphoma.
Highlights
Mucosa-associated lymphoid tissue (MALT) lymphoma is a distinct subgroup of non-Hodgkin’s lymphoma (NHL) that comprises more than two-thirds of all primary NHL of the lung [1]; primary tracheal MALT lymphoma is quite rare
This is the first report of primary tracheal MALT lymphoma in China that was successfully treated with temporary tracheal stent insertion guided by bronchoscopy and systemic chemotherapy
The tracheal stent was extracted after 35 days after the patient had been given one course of chemotherapy
Summary
Mucosa-associated lymphoid tissue (MALT) lymphoma is a distinct subgroup of non-Hodgkin’s lymphoma (NHL) that comprises more than two-thirds of all primary NHL of the lung [1]; primary tracheal MALT lymphoma is quite rare. Chemotherapy, and radiation therapy usually are selected according to the clinical stage. This is the first report of primary tracheal MALT lymphoma in China that was successfully treated with temporary tracheal stent insertion guided by bronchoscopy and systemic chemotherapy. Case presentation A 49-year-old woman was referred to our hospital with the complaint of dyspnea for 4 years and increasing symptoms over the last 2 months. She did not present with night sweats or fever. The patient received a bone marrow biopsy, a gastric fibroscopy, and a color Doppler ultrasound of the neck. The patient has been well without any symptoms of recurrence for 12 months since the initial diagnosis
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