Abstract
During follow-up of a 2012 US outbreak of lymphocytic choriomeningitis virus (LCMV), we conducted a trace-forward investigation. LCMV-infected feeder mice originating from a US rodent breeding facility had been distributed to >500 locations in 21 states. All mice from the facility were euthanized, and no additional persons tested positive for LCMV infection.
Highlights
During follow-up of a 2012 US outbreak of lymphocytic choriomeningitis virus (LCMV), we conducted a traceforward investigation
LCMV aseptic meningitis was diagnosed in 4 employees, and diagnostic testing of the breeding population identified LCMV infection among mice but not rats; no hamsters were bred at the facility
We describe the trace-forward investigation of live mice distributed by facility B and the public health measures taken to prevent additional human LCMV infections
Summary
During follow-up of a 2012 US outbreak of lymphocytic choriomeningitis virus (LCMV), we conducted a traceforward investigation. During summer 2012, state and local agencies and the Centers for Disease Control and Prevention (CDC; Atlanta, GA, USA) investigated an outbreak of LCMV in the United States. A total of 31 (32%) of 97 tested employees of 3 rodent breeding facilities were infected because of the likely introduction of LCMV into the captive breeding population by wild mice.
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