Abstract
Pre-column derivatization of the primary hydroxyl group in fatty alcohols and fatty alcohol ethoxylates using carbazole-9-carbonyl chloride (CC−Cl) and FMOC-Cl is described and compared with derivatization with 1-naphthoyl chloride (N−Cl). As the excess of derivatization reagent leads to a broad and strongly tailing reagent peak, it hinders trace determination of fatty alcohols and fatty alcohol ethoxylates. Therefore, an off-line as well as an on-line solid-phase extraction (SPE) method for removal of excess reagent are described. The on-line method which is based on column switching, shows better reproducibility higher pre-concentration, lower risk of contamination and can be easily automated, while the off-line method is better suited for the analysis of derivatized, fatty alcohol ethoxylates. An example of the trace analysis of fatty alcohols with a concentration of 2 ppb is given.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
