Trace amine-associated receptors and adult neurogenesis

Abstract

Trace amine-associated receptors (TAARs) are a class of sensory G protein-coupled receptors that detect amines, products of decarboxylation of amino acids. The majority of TAARs (TAAR2-TAAR9) have been described in the olfactory epithelium and considered to be olfactory receptors sensing innate odors. However, there is evidence that one of the members of this family, TAAR5, is expressed also in the limbic areas of the brain receiving projection from the olfactory system and involved in the regulation of emotional behaviors.