Abstract
目的 观察小梁切除术联合丝裂霉素C(MMC)治疗儿童青光眼的疗效和安全性.方法小梁切除术联合MMC治疗儿童青光眼32例(32眼)年龄3～14岁.术后随访时间6～40月(平均18.07±5.81月),对眼压、视力和并发症进行了分析,以Kaplan-Meier寿命表判断成功率.结果相对成功率标准为:眼压6～21 mmHg,不用或用抗青光眼药物,不需要再进行抗青光眼手术,并且未发生严重的并发症.6月累积成功率为85.47%(n=32),12月为76.32%(n=25),24月为64.29%(n=12).并发症包括浅前房6眼、薄壁滤过泡5眼、滤过泡渗漏3眼、囊样滤过泡2眼、低眼压2眼、滤过泡炎1眼、白内障1眼和视网膜脱离1眼.结论小梁切除术联合MMC可能是治疗儿童青光眼一种有效的方法.然而,MMC术后薄壁滤过泡和滤过泡相关的感染以及其他问题尚需长期随访。
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