Abstract
Reduced bone quality appears to contribute to the increased fracture risk in individuals with type 1 diabetes (T1D). Advanced glycation end products (AGEs) tissue accumulation, which reflects long-term glycemic control, may influence bone quality in T1D. We aimed to determine if skin AGEs, as a surrogate marker for bone AGEs, are associated with trabecular bone score (TBS), an index of bone microarchitecture derived from lumbar spine DXA images.
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