TP011/#1536 A double-blind placebo-controlled phase III chemo-immunotherapy (Paclitaxel-carboplatin-oregovomab [PCO]) vs chemotherapy (Paclitaxel-carboplatin-placebo [PCP]) in patients with newly diagnosed, advanced epithelial ovarian cancer (EOC): FLORA-5/GOG-3035 study

Abstract

IntroductionOregovomab, a murine IgGκ1 MAb, binds to the circulating tumor associated antigen CA125, resulting in development of immunogenic complexes with CA125, which are subsequently processed by dendritic cells and macrophages...