Abstract
Tracing the etiology of paediatric neurological disorders back to toxoplasmosis was often difficultand particularly challenged, depended mainly on serology in common practice. The currentstudy evaluated the role of toxoplasmosis and oxidative stress in Egyptian children sufferingfrom acute neurodevelopmental disorders, by seroprevalence in relation to IFN gamma in patientswith positivity for IgG & IgM. The result showed that out of 155 patients, 128 (82.6%)were positive for IgG and 10 (6.5%) were positive for both IgG & IgM. Also, the serummalondialdehyde (MDA) was significantly higher in seropositive pa-tients than in seronegativeones. Six children suffered from acute toxoplasmosis showed high levels of serum IFN gamma.
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