Toxicology of the Lung

Abstract

Methodologies and technology for animal inhalation toxicology studies nasal structure, function, and toxicology gross morphometry of airways cell populations and structure-function relationships of cells in the airways morphometric analysis of the gas exchange region of the lung three- dimensional analysis of lung structure and its application to pulmonary Dosimetry Models Metabolism Of Xenobiotics The Respiratory Tract extrapolation of animal data to humans - homology of pulmonary physiological responses with ozone exposure biological markers of respiratory tract exposure quantitative clinical studies with defined exposure atmospheres the epidemiologic approach to investigating indoor and outdoor air pollution cellular approaches in respiratory tract toxicology pulmonary reactions and mechanisms of toxicity of inhaled fibres immunological responses within the lung after inhalation of airborne chemicals chemically-induced pulmonary hypersensitivity, airway hyperactivity and asthma chronic inhalation bioassays for respiratory tract carcinogenesis advances in physiological modelling approaches for understanding the disposition of inhaled vapours regional respiratory tract absorption of inhaled reactive gases approaches to modelling disposition of inhaled particles and fibres in the lung developing risk assessments for airborne materials.