Abstract

Mushrooms account for a part of human diet due to their exquisite taste and protein content as well as their promising health effects unveiled by scientific research. Toxic and non-toxic mushrooms frequently share considerable morphological similarities, which mislead the collectors/consumers, resulting in mycotoxicity. Numerous mushroom species are considered "poisonous" as they produce dangerous toxins. For instance, members of the genus Amanita, especially A. phalloides, A. virosa and A. verna, are responsible for severe and even life-threatening noxious consequences. Globally, mushroom poisoning is a crucial healthcare issue as it leads to a considerable number of deaths annually. However, no definite antidote has been introduced to treat this poisoning. The present article discusses the characteristics of A. virosa in terms of epidemiology, mechanisms of toxicity, poisoning features and management.

Highlights

  • Mushrooms are increasingly found in human diet due to their exquisite taste and protein content as well as their health-promoting effects revealed by numerous scientific studies [1,2,3,4,5,6]

  • In the most recent outbreak of mushroom poisoning in Iran, 1200 intoxicated individuals were referred to hospitals in 13 Western and Northwestern cities of Iran [25]

  • Major toxin classes found in the genus Amanita are amatoxins, phallotoxins and virotoxins, all classified as cyclopeptides with a sulfur-linked tryptophan and some unusual hydroxylated amino-acids [51]

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Summary

Introduction

Mushrooms are increasingly found in human diet due to their exquisite taste and protein content as well as their health-promoting effects revealed by numerous scientific studies [1,2,3,4,5,6]. In this regard, several pharmacologically active compounds have been characterized in mushrooms [7]. Profile, we aimed to review the toxic effects of Amanita mushrooms, with a special focus on A. virosa

Epidemiology of mushroom poisonings
Classification and toxicity of Amanita mushrooms
Toxins of Amanita mushrooms and mechanisms of toxicity
Toxic features and management
Conclusions
Findings
Conflicts of interest
Full Text
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