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Abstract
Medicinal plants are highly investigated due to their multiple effects in human health. In the last two decades, plants belonging to Lamiaceae family have emerged as an important source of compounds with beneficial effects in various pathologies. Many species of the Lamiaceae family have a high volatile oil content which can be found in different parts of the plant. Some representative examples include Lavandula spp. Salvia spp. and Mentha spp. which are species with essential oils studied for antioxidant, antimicrobial and antitumor effects. The aim of this study was to evaluate the effect of six essential oils at skin level before and after encapsulation in hydroxypropyl-gamma-cyclodextrins. Results indicated that regardless of the tested form, the samples did not display an irritating or toxic effect at skin level, suggesting that the essential oils can be used in different formulations for topical application. Keywords: essential oils, Lamiaceae, hydroxypropyl-gamma-cyclodextrins, mexametry, corneometry, tewametry
Highlights
Medicinal plants are highly investigated due to their multiple effects in human health
According to Cavanagh et al, lavender essential oils (EO) is used in numerous dermatological conditions such as dermatitis, eczema and psoriasis, but they pointed that there are studies showing that exposure to lavender oil can produce dermatitis [6]
EO obtained from Salvia sclarea L. are used in both the cosmetics and food industry
Summary
Medicinal plants are highly investigated due to their multiple effects in human health. The present study was aimed to provide a toxicological evaluation of some essential oils obtained from Lavandula spp. Salvia spp. and Mentha spp, belonging to the Lamiaceae family and harvested from Romania and to establish their effects at skin level after encapsulation in hydroxypropyl-gamma-cyclodextrins.
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