Abstract
Twelve age-matched healthy adult male Chinchilla rabbits (2.0 ± 0.5 kg BW) were divided into three equal groups (two treatment and one control groups). The treatment groups were given 2.5 mL and 5.0 mL of aqueous extract of the leaves of Moringa oleifera and Caulis bambusae by oral intubation, while the control group received 5.0 mL of the vehicle of extraction (sterile distilled water) and examined for 30 days. The effects of the leave extracts on the heamatological parameters, selected liver enzymes, insulin level and body weights of the affected rabbits were analyzed. There were significant increases in CD 4 cells (p<0.01), lymphocytes (p<0.05) and a decrease in neutrophils (p<0.05). There was an enhancement in the activities of acid phosphatase, alkaline phosphatase, aspartate transaminase and alanine transaminase in rabbits exposed to 2.5 mL of the extract. There was no significant difference in the histology of major organs, weights and the physical and behavioral pattern of both test and control rabbits.
Highlights
The plant Moringa oleifera Lam. commonly called drum stick plant or horse radish plant or miracle plant or mother’s best friend is the most widely cultivated species of the monogeneric family Moringaceae, which includes 13 species of trees and shrubs distributed in sub-Himalayan ranges of India, Sri Lanka, north-eastern and south–western Africa, Madagascar and Arabia [1]
The pulverized leaves of M. oleifera and C. bambusae were obtained from the National Academy for the Advancement of Science (NAAS), Benin City, Nigeria
The impact of extract of M. oleifera and C. bambusae on rabbits was determined in this study using short-term investigation protocol
Summary
The plant Moringa oleifera Lam. commonly called drum stick plant or horse radish plant or miracle plant or mother’s best friend is the most widely cultivated species of the monogeneric family Moringaceae (order Brassicales), which includes 13 species of trees and shrubs distributed in sub-Himalayan ranges of India, Sri Lanka, north-eastern and south–western Africa, Madagascar and Arabia [1]. The Moringa tree is a multi-function plant It has been cultivated in tropical regions all over the world for high protein, vitamins, minerals and carbohydrate content of entire plant; high value of nutrition for both humans and livestock; high oil content (30-42%) of the seeds which is edible and with medicinal uses; and for its seeds coagulant properties for water and wastewater treatment [2]. This plant has been well documented for its medicinal importance for a long time. In Malaysia, the young tender pods are cut into small pieces and added to curries for seasoning [3]
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