Toxicokinetics of DDE, Benzo(a)Pyrene, and 2, 4, 5, 2′, 4′, 5′-Hexachlorobiphenyl in Pontoporeia Hoyi and Mysis Relicta

Abstract

The toxicokinetics of DDE, benzo(a)pyrene (BaP), and 2, 4, 5, 2’, 4’, 5’-hexachlorobiphenyl (HB) were followed for the amphipod, Pontoporeia hoyi, and the mysid, Mysis relicta. Pontoporeia and Mysis had similar uptake clearances (K u) for DDE (mean = 79.2 mL/g/h and 46.0 mL/g/h, respectively), BaP (mean = 75.9 mL/g/h and 39.9 mL/g/h, respectively), and HB (mean = 53.5 mL/g/h and 57.5 mL/g/hr, respectively) compounds with log octanol-water partition coefficients (K ow's) ranging from 5.7 to 6.7. Amphipods and mysids were most efficient at eliminating BaP (mean K d = −0.0017/h and −0.0047/h, respectively) and least efficient at eliminating HB (mean = −0.0008/h and −0.0001/h respectively). Amphipods were more efficient than mysids in eliminating DDE (mean = −0.0010/h and −0.0005/h, respectively) and HB while mysids were more efficient at eliminating BaP. Because K d's for DDE, BaP, and HB were substantially different between P. hoyi and M. relicta, there were substantial differences in the calculated bioconcentration factors (BCFs). Amphipods tended toward larger BCFs than mysids for BaP (mean = 48,582 and 8,496, respectively) but lower BCFs for DDE (mean = 95,629 and 138,760, respectively) and HB (mean = 101,663 and 442,231, respectively) than mysids.