Abstract
Mentawan plant (Poikilospermum suaveolens Blume Merr) is a species of the genus poikilospermum, including the urticaceae family, which is traditionally used by the community for medicine. This plant has the ability to treat eye diseases, fever, malaria and itching and has the potential as an anticancer. This research method includes extraction, fractionation, and fraction bioactivity test with the brine shrimp lethality test (BSLT) against Artemia salina. From the results of the toxicity test using the BSLT method, the activity of methanol fractions with LC50 values were 4,8752; 62,8492; 85,5460; 45,7088; 28,1838; 11,985; 33.2123 µg / mL. Based on the LC50 value, it could be concluded that mentawan plant has potential as anticancer.
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