TOXICITY TEST (LD-50) of HERBAL PREPARATIONS Nepenthes ampularia AS The STANDARD of SECURITY of JAMU HYPERTENSION

Abstract

The excavation of the potential utilization of herbs as a plant biopharma or as a material to manufacture. There is empirical evidence that Nepenthes has been used as a lowering of hypertension by taking a decoction of its pitchers. For the use and utilization as a medicinal plant need to be done research that refers to the scientifically certified Jamu. The research aims to detect acute toxic effects so that can be obtained the water safety overview Nepenthes pitchers. The toxicity test was carried out by the Brine Shrimp Lethality Test (BSLT), Artemia salina larva with four extract concentrations (0, 10, 500, 1000 ppm). Based on the results of toxic tests showed that the death rate of A. salina at all levels of concentration is 0 deaths. It is evidence that Nepenthes ampularia is not toxic to A. salina..