Abstract
The bacterial growth inhibition test was used to determine toxicity of the halogenated aromatics on the mixed bacteria from the Yangtze River. The concentration values causing 50% reduction of bacteria growth for 24 hr (IC50) and the maximum tolerance concentration for 7 d (MATC) were gained according to the concentration-response curves. An obvious linear relationship was found between the two toxicity descriptors. The following quantitative structure- activity relationships were developed by using the valence molecular connectivity index method: -lgIC50=0.8266Xpcv- 0.2363Xpv+3.811 (R2=0.833) and -lgMATC=1.2016Xpcv-0.3783Xpv+4.614 (R2=0.900). The two equations were found to fit well. It suggested that the models derived from the molecular connectivity index could be used successfully to predict the toxicity of halogenated aromatic compounds.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
