Abstract
Evidence of hepatotoxicity was not found in Sprague-Dawley rats given sodium pantothenate, d-panthenol, or d-pantethine intramuscularly in doses ranging from 0.2 g/kg to 2.0 g/kg. A slight increase in the amount of liver lipid deposition was observed in the rats weighing 110–120 g which were given 0.2 g/kg and 2.0 g/kg of d-panthenol, but not in rats weighing 220–275 g.
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