Abstract

Study on toxicity test of n-hexane extract of mundar (Garcinia forbesii King) fruit skin has been conducted, By BSLT method. A. salina larvae used to determine LC50 value. The weight of n-hexane extract obtained was 20.69 g from 405.64 g of dried mundar fruit skin sample. The yield of n-hexane extract of mundar fruit skin was 5.10%. N-hexane extract of mundar fruit skin is very toxic, the LC50 value obtained was 9.753 ppm.

Highlights

  • The Garcinia genus has been known and used by the Indonesian people as a source of edible fruits and medicinal plants

  • Mangostana L.) is one of the species of the genus Garcinia that has been traditionally used by Indonesian people as a medicinal plant

  • The solvent was separated from the extract by the evaporation method using a rotary vacuum evaporator, the temperature was maintained at 40 ° C to obtain concentrated n-hexane extract from the mundar pericarp

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Summary

Introduction

The Garcinia genus has been known and used by the Indonesian people as a source of edible fruits and medicinal plants. Mangostana L.) is one of the species of the genus Garcinia that has been traditionally used by Indonesian people as a medicinal plant. The secondary metabolite compounds in the Garcinia genus include flavonoids, tannins and, saponins [3], which have bioactivity as antibacterial, anticancer, and anti-inflammatory [4]. Brine Shrimp Lethality Test (BSLT) is a simple bioassay method to explore active compounds or active extracts from secondary metabolites of natural substances from fungi, molds, herbs, higher plants and animals [9,10]. The potential of active compounds in mundar rind and its toxicity is unknown, research is needed to determine the toxicity level of N-hexane pericarp mundar extract using Brine Shrimp Lethality Test (BSLT)

Extraction of plant material
Toxicity test
The hatching of shrimp larvae
Procedure of toxicity test methods using BSLT
Results and Discussion
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