Abstract
Nanosilver (nAg) is increasingly being used in a wide array of fields, and its toxicity has been extensively studied. Here we present a review of environmental nAg cytotoxicity, as well toxicity mechanisms. The cytotoxicity is described in four aspects including cell membrane, the genome, the mitochondria and autophagy flux. Considering its broad-spectrum antibiotic effects, nAg ecotoxicity is described, in addition to an analysis of factors necessary in controlling its toxicity. We propose a toxicity assessment model with potential applications to living organisms, based on the antibacterial effects of nAg.
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