Abstract
When specimens of Helisoma anceps were exposed to water containing 0.1, 1, and 5 ppm cadmium, mortality was proportional to concentration but tissue levels of Cd were not. The shell was the site of highest concentration and total amount of Cd due to adsorption and active accumulation. Concentrations of Cd in the kidney and mantle were equal to or greater than the remaining soft tissue. Ultrastructural changes in the kidney associated with Cd exposure were almost exclusively confined to the nephrocytes. Graded transformation of the residual body to a secondary lysosome was proportional to the Cd concentration of the medium and length of exposure. Atypical nucleoli and reticular bodies appeared in the 1-ppm Cd dose. Only after autolysis of the nephrocytes in 5 ppm did ultrastructural changes occur in the ureter cells. Ultrastructural changes in the kidney epithelia were proportional to Cd dosage but were not necessarily indicative of the tissue burden of Cd.
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