Abstract

Polyhedral formulations based on Rasayana therapy described in Charaka Samhita showed remarkable improvement in quality of life of various cancer patients who have been found to be refractory or poor responders to modern chemotherapy and radiation treatment. One of the most recent novel herbomineral preparation, Las01 prepared absolutely as per the instruction given in the ancient Ayurvedic literature has been found to be effective as a potent anticancer drug in the human cell lines, the MCF-7 and Hela cancer cell lines. This novel preparation of Las01 is also found to be devoid of toxicity both in animals as well as in human subjects, which is the main drawback of chemotherapeutic agents used in modern system of medicine. Our results warrant multicentric clinical trials on a large scale which seems to be a future promising drug to cure incurables cancer patients.

Highlights

  • Cancer has become one of the biggest challenges to the scientific community over the world, and despite development of drugs and other modalities for treatment of Cancer, there are complexities at every level of treatment

  • Our present study demonstrates the efficacy of Las01 in in vitro tests on human cervical cancer cell line (HeLa) and breast cancer cell line and the safety of Las01 on variety of haematological and biochemical parameters both in animal experiments as well as in human beings

  • One of the most recent novel Herbomineral preparations, Las01, prepared absolutely as per the instruction given in LFT Serum bilirubin (T) Serum bilirubin (D) Bilirubin (ID) Serum glutamate oxaloacetate transaminase (SGOT) serum glutamate pyruvate transaminase (SGPT) S-Alkaline phosphatase

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Summary

Introduction

Cancer has become one of the biggest challenges to the scientific community over the world, and despite development of drugs and other modalities for treatment of Cancer, there are complexities at every level of treatment. There is need to find out relatively safe, effective, and economical solution for cancer. The branch of Ayurveda deals with medicinal properties of herbometallic and herbomineral preparations known as Rasa shastra and the drugs which are used are known as Rasa Aushadhi. They were more popular during the period of Lord Buddha due to its faster relief, lesser and convenient doses, and mysterious efficacy as compared to only herbal drugs. Various constituents of Herbomineral compounds such as gold, silver, lead, iron, and arsenic are never used in the raw form as their raw form causes poisonous and toxic effects [2]

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