Abstract
The toxicity and OSHA regulations for the solvents evolved in histological operations are reviewed. In the laboratory, technical operations use hazardous solvents in various areas. Conventional ventilation installations are costly, difficult to balance and the resulting air emissions are subject to governmental pollution regulations.A multidisciplinary team (histologists, environmental engineers and pathologists) developed an inexpensive, effective and lightweight adsorbent/enclosure for high risk areas in the histology laboratory. Removal performance for formaldehyde, xylene and isopropyl alcohol was determined by gas chromatographic analysis. The adsorbent filter developed reduced formaldehyde, xylene and isopropyl alcohol levels well below OSHA safe level requirements in the laboratory.A scavenger adsorbent unit was built for reducing accumulation of room or storage area residual solvent concentrations. Other specific point source adsorbent enclosures are being developed and tested for histology operations.
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