Abstract

A little over five years ago, following the widespread dissemination of the results of epidemiologic studies linking menstrual toxic shock syndrome (TSS) to the use of tampons, many women switched to other forms of menstrual protection. As a result, the percentage of menstruating women who used tampons fell from 70% to 49%. In addition, the manufacturer of a single brand of tampons withdrew its product from the market after further studies demonstrated that users of that brand were at increased risk of developing menstrual TSS compared with users of other brands. In these studies, the relative risks or odds ratios (the extent to which users of a given product were at increased risk of developing TSS, compared with nonusers) were in the range of 8 to 30. Thus, tampon users in general were approximately 18 times as likely to develop menstrual TSS as nonusers, 1 and users of Rely brand

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