Abstract
THIS work began in Cambridge in 1939 with the original purpose of preparing compounds of the type PbiR4 which might be toxic by inhalation. It should be noted that, at that time, supplies of arsenic in Great Britain were very much reduced, whereas lead was readily available. Compounds which we contemplated preparing were (C2H5)2Pb(CH2CH = CH2)2, (C2H5)2Pb(CH2CH2Cl)2 and Pb(CH2CH2Cl)4, etc. As an intermediate, it was necessaryto prepare triethyl lead chloride (C2H5)3PbCl in quantity, and one of us (B. C. S.), while working with thiscompound, developed the symptoms of a severe attack ofinfluenza, which, however, wore off at night and returned during the day. The compound was therefore tested for sternutatory properties, and found to produce, at a concentration of one part in a million, an atmosphere in which respiration was difficult.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.